--- title: View of Field (3) description: QUEL Imaging's observations of challenges with in vivo fluorescence imaging. How can phantoms and reference targets be used to advance the field? (3) --- [Skip to content](https://blog.quelimaging.com/page/3#main-content) [![QUEL\_web\_logo-1](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_web_logo-1.png?width=200&height=75&name=QUEL_web_logo-1.png)](https://www.QUELimaging.com) - [Home](https://blog.quelimaging.com) - [Products](https://shop.QUELimaging.com) - [Blog](https://blog.quelimaging.com) - [News](https://www.QUELimaging.com/news) - [About](https://www.quelimaging.com/about) - [Resources](https://shop.QUELimaging.com/Resources) Open main navigation Close main navigation - [Home](https://blog.quelimaging.com) - [Products](https://shop.QUELimaging.com) - [Blog](https://blog.quelimaging.com) - [News](https://www.QUELimaging.com/news) - [About](https://www.quelimaging.com/about) - [Resources](https://shop.QUELimaging.com/Resources) # View of Field ### Reflections on the field of *in vivo* fluorescence imaging [![Illustration of how green and red light will scatter and absorb differently in tissue. ](https://blog.quelimaging.com/hubfs/undefined-Oct-13-2025-05-56-25-7121-PM.png)](https://blog.quelimaging.com/light-tissue-interaction-overview) [concepts](https://blog.quelimaging.com/tag/concepts) ### [Light-Tissue Interactions in Optical Medical Devices](https://blog.quelimaging.com/light-tissue-interaction-overview) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) When you're developing medical imaging systems, one of the biggest challenges is understanding how... [Read more](https://blog.quelimaging.com/light-tissue-interaction-overview) [![](https://blog.quelimaging.com/hubfs/undefined-Oct-20-2025-07-18-36-4894-PM.png)](https://blog.quelimaging.com/introducing-optiblox) [optical properties](https://blog.quelimaging.com/tag/optical-properties) ### [Introducing OptiBlox® - the latest in optical tissue phantom technology](https://blog.quelimaging.com/introducing-optiblox) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) Across optical sensing applications—from medical-grade pulse oximetry and surgical imaging to... [Read more](https://blog.quelimaging.com/introducing-optiblox) [![](https://blog.quelimaging.com/hubfs/CoinCover_example_Inferno.jpg)](https://blog.quelimaging.com/tips-tricks-developing-a-fluorescence-imaging-system) [fluorescenceimaging](https://blog.quelimaging.com/tag/fluorescenceimaging) ### [Tips & Tricks: Developing a fluorescence imaging system](https://blog.quelimaging.com/tips-tricks-developing-a-fluorescence-imaging-system) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) Weak and noisy fluorescence images can kill user confidence in your medical device. Sometimes it’s... [Read more](https://blog.quelimaging.com/tips-tricks-developing-a-fluorescence-imaging-system) [![Webinar Panelists surrounding the QUEL Imaging logo](https://blog.quelimaging.com/hubfs/FF8FA85E-C2FC-44F9-B4EE-0A50A3ACC031.png)](https://blog.quelimaging.com/blaze-webinar-202507) [imageguidedsurgery](https://blog.quelimaging.com/tag/imageguidedsurgery) ### [Accelerating Surgical Imaging: Webinar with Blaze Bioscience](https://blog.quelimaging.com/blaze-webinar-202507) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) [Blaze Bioscience](https://www.blazebioscience.com/technology) is developing a real-time surgical imaging system that highlights [tozuleristide](https://pmc.ncbi.nlm.nih.gov/articles/PMC8355837/#:~:text=BLZ%2D100%20(tozuleristide)%20is%20an%20intraoperative%20fluorescent%20imaging,used%20in%20real%20time%20to%20guide%20tumor)... [Read more](https://blog.quelimaging.com/blaze-webinar-202507) [![QUEL Imaging Q800 reference target family](https://blog.quelimaging.com/hubfs/VISIMG-S_r0-0_REF-FAMILY-Q800.jpg)](https://blog.quelimaging.com/fda-draft-guidance) [standardization](https://blog.quelimaging.com/tag/standardization) ### [FDA issues draft guidance on optical imaging drugs](https://blog.quelimaging.com/fda-draft-guidance) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) The FDA recently released [draft guidance for optical imaging drugs](https://www.fda.gov/media/184943/download), including an appendix dedicated... [Read more](https://blog.quelimaging.com/fda-draft-guidance) [![QUELImaging.com core services: Fluorescence Imaging Systems, Fluorescent Probe Characterization, Custom Design & Manufacturing Services, Optical Material Development](https://blog.quelimaging.com/hubfs/QUEL-Imaging_core_services.png)](https://blog.quelimaging.com/innovations-into-impact) [clinical translation](https://blog.quelimaging.com/tag/clinical-translation) ### [Partnering with QUEL Imaging - Turning Innovations into Impact](https://blog.quelimaging.com/innovations-into-impact) ![Picture of Ethan LaRochelle](https://app.hubspot.com/settings/avatar/925081a77283a399dbd145b49b251212) [Ethan LaRochelle](https://blog.quelimaging.com/author/ethan) QUEL Imaging was founded with support from the NIH SBIR program — a critical funding mechanism for... [Read more](https://blog.quelimaging.com/innovations-into-impact) [![Serial dilutions in 2016](https://blog.quelimaging.com/hubfs/Phantoms-2016.jpg)](https://blog.quelimaging.com/back-to-the-future) [standardization](https://blog.quelimaging.com/tag/standardization) ### [Back to the Future: From Telesurgery to Translational Tools](https://blog.quelimaging.com/back-to-the-future) ![Picture of Ethan LaRochelle](https://app.hubspot.com/settings/avatar/925081a77283a399dbd145b49b251212) [Ethan LaRochelle](https://blog.quelimaging.com/author/ethan) After a week at the [Hamlyn Symposium on Medical Robotics](https://www.hamlynsymposium.org/programme-2025/), I’ve been reflecting on this year’s... [Read more](https://blog.quelimaging.com/back-to-the-future) [![](https://blog.quelimaging.com/hubfs/Distortion.gif)](https://blog.quelimaging.com/distortion-intro) [use-guide](https://blog.quelimaging.com/tag/use-guide) ### [Distortion: Anatomy of Accurate Imaging (Part 2)](https://blog.quelimaging.com/distortion-intro) ![Picture of Guest post by Christie Lin](https://blog.quelimaging.com/hs-fs/hubfs/ChristieLin.jpeg?width=50&name=ChristieLin.jpeg) [Guest post by Christie Lin](https://blog.quelimaging.com/author/christie-lin) Image distortion is a critical determinant of image fidelity and quantifies the geometric accuracy... [Read more](https://blog.quelimaging.com/distortion-intro) [![Animation showing fluorescence image with non-uniform illumination and collection](https://blog.quelimaging.com/hubfs/QUEL_E_RUD_animation.gif)](https://blog.quelimaging.com/fluorescence-uniformity-intro) [use-guide](https://blog.quelimaging.com/tag/use-guide) ### [Fluorescence Uniformity: Anatomy of Accurate Imaging (Part 1)](https://blog.quelimaging.com/fluorescence-uniformity-intro) ![Picture of Guest post by Christie Lin](https://blog.quelimaging.com/hs-fs/hubfs/ChristieLin.jpeg?width=50&name=ChristieLin.jpeg) [Guest post by Christie Lin](https://blog.quelimaging.com/author/christie-lin) *Imaging performance* can be assessed in many ways, but two of the most critical aspects are how... [Read more](https://blog.quelimaging.com/fluorescence-uniformity-intro) [![Stitched image showing RET target illumination moving across the field of view](https://blog.quelimaging.com/hubfs/QUEL_RET_Grid.gif)](https://blog.quelimaging.com/capture-eval-with-ret) [use-guide](https://blog.quelimaging.com/tag/use-guide) ### [Decoupling Excitation & Detection: Radiometric Emitter Targets](https://blog.quelimaging.com/capture-eval-with-ret) ![Picture of Guest post by Christie Lin](https://blog.quelimaging.com/hs-fs/hubfs/ChristieLin.jpeg?width=50&name=ChristieLin.jpeg) [Guest post by Christie Lin](https://blog.quelimaging.com/author/christie-lin) In the world of fluorescence imaging, both excitation intensity and emission detection sensitivity... 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