--- title: View of Field (2) description: QUEL Imaging's observations of challenges with in vivo fluorescence imaging. How can phantoms and reference targets be used to advance the field? (2) --- [Skip to content](https://blog.quelimaging.com/page/2#main-content) [![QUEL\_web\_logo-1](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_web_logo-1.png?width=200&height=75&name=QUEL_web_logo-1.png)](https://www.QUELimaging.com) - [Home](https://blog.quelimaging.com) - [Products](https://shop.QUELimaging.com) - [Blog](https://blog.quelimaging.com) - [News](https://www.QUELimaging.com/news) - [About](https://www.quelimaging.com/about) - [Resources](https://shop.QUELimaging.com/Resources) Open main navigation Close main navigation - [Home](https://blog.quelimaging.com) - [Products](https://shop.QUELimaging.com) - [Blog](https://blog.quelimaging.com) - [News](https://www.QUELimaging.com/news) - [About](https://www.quelimaging.com/about) - [Resources](https://shop.QUELimaging.com/Resources) # View of Field ### Reflections on the field of *in vivo* fluorescence imaging [![Alberto Ruiz, PhD (CTO & co-founder, QUEL Imaging)](https://blog.quelimaging.com/hubfs/AlbertoRuiz.gif)](https://blog.quelimaging.com/2025-11-phantoms-in-fgs) [fluorescenceimaging](https://blog.quelimaging.com/tag/fluorescenceimaging) ### [Dive Into Fluorescence-Guided Surgery: Highlights From OPTICA's Optical Phantom Webinar Series](https://blog.quelimaging.com/2025-11-phantoms-in-fgs) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) Fluorescence-guided surgery (FGS) continues to shape the future of precision medicine, and... [Read more](https://blog.quelimaging.com/2025-11-phantoms-in-fgs) [![Painting of UPenn surgical amphitheatre from mid-late 1800s](https://blog.quelimaging.com/hubfs/20251113_203337~2.jpg)](https://blog.quelimaging.com/penn-psimi-2025) [surgery](https://blog.quelimaging.com/tag/surgery) ### [Precision Surgery, Fluorescence, and the Road to Real-World Adoption](https://blog.quelimaging.com/penn-psimi-2025) ![Picture of Ethan LaRochelle](https://app.hubspot.com/settings/avatar/925081a77283a399dbd145b49b251212) [Ethan LaRochelle](https://blog.quelimaging.com/author/ethan) *A recap from the “Precision Surgery Intraoperative Molecular Imaging: 4th Clinical Trials Update”...* [Read more](https://blog.quelimaging.com/penn-psimi-2025) [![Animation showing Gaussian Splat of the Prototype FluoFlow Colon Phantom](https://blog.quelimaging.com/hubfs/QUEL_FluoFlowColon.gif)](https://blog.quelimaging.com/3dgs-opsiclear-quel) [concepts](https://blog.quelimaging.com/tag/concepts) ### [3D Gaussian Splatting and Future Digital Twins](https://blog.quelimaging.com/3dgs-opsiclear-quel) ![Picture of Ethan LaRochelle](https://app.hubspot.com/settings/avatar/925081a77283a399dbd145b49b251212) [Ethan LaRochelle](https://blog.quelimaging.com/author/ethan) This week, we shared a five-day series of 3D Gaussian splats created in collaboration with [OpsiClear](https://www.opsiclear.com/) [Read more](https://blog.quelimaging.com/3dgs-opsiclear-quel) [![Maple syrup samples under UV light](https://blog.quelimaging.com/hubfs/Screenshot%202025-11-03%20at%204.08.06%20PM.png)](https://blog.quelimaging.com/maple-syrup) [fluorescenceimaging](https://blog.quelimaging.com/tag/fluorescenceimaging) ### [Optical Properties in Action - Maple Syrup](https://blog.quelimaging.com/maple-syrup) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) The official Flavor of Vermont is Maple, and our State Tree is the Sugar Maple. There’s a friendly... [Read more](https://blog.quelimaging.com/maple-syrup) [![QUEL Imaging team in DC for NVIDIA GTC 2025](https://blog.quelimaging.com/hubfs/IMG_9120-1.jpeg)](https://blog.quelimaging.com/phantoms-for-truth) [conferences](https://blog.quelimaging.com/tag/conferences) ### [Optical Phantoms in the Age of AI Factories](https://blog.quelimaging.com/phantoms-for-truth) ![Picture of Ethan LaRochelle](https://app.hubspot.com/settings/avatar/925081a77283a399dbd145b49b251212) [Ethan LaRochelle](https://blog.quelimaging.com/author/ethan) At QUEL Imaging, our mission has always been to accelerate the clinical translation of biomedical... [Read more](https://blog.quelimaging.com/phantoms-for-truth) [![Q-S Optiblox Product Demonstration illuminated with red and green lasers](https://blog.quelimaging.com/hubfs/Screenshot%202025-10-24%20at%2012.19.11%20PM.png)](https://blog.quelimaging.com/optiblox-qs-overview) [optical properties](https://blog.quelimaging.com/tag/optical-properties) ### [Soft Tissue Phantoms for Medical Device Development: Unlocking Tissue Compliance](https://blog.quelimaging.com/optiblox-qs-overview) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) When you press a pulse oximeter against your finger, the tissue deforms. When a surgeon navigates... [Read more](https://blog.quelimaging.com/optiblox-qs-overview) [![QUEL Imaging's Skin Tone Multi-material Phantom](https://blog.quelimaging.com/hubfs/Screenshot%202025-10-27%20at%209.37.18%20AM.png)](https://blog.quelimaging.com/optiblox-qx-overview) [optical properties](https://blog.quelimaging.com/tag/optical-properties) ### [Heterogeneous Optical Tissue Phantoms using Multi-Material Manufacturing](https://blog.quelimaging.com/optiblox-qx-overview) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) Traditional optical phantoms have limitations. They're homogeneous blocks of material with uniform... [Read more](https://blog.quelimaging.com/optiblox-qx-overview) [![Conceptual schematic of photon time-of-flight detection](https://blog.quelimaging.com/hubfs/undefined-Oct-17-2025-08-58-57-2454-PM.png)](https://blog.quelimaging.com/tof-intro) [concepts](https://blog.quelimaging.com/tag/concepts) ### [Photon Time-of-Flight Measurements for Tissue Optical Properties](https://blog.quelimaging.com/tof-intro) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) When light travels through air or space, it moves unimaginably fast—circling the Earth about seven... [Read more](https://blog.quelimaging.com/tof-intro) [![Animation illustrating optical transmission, scattering, and absorption in a tissue-mimicking sample. ](https://blog.quelimaging.com/hubfs/undefined-Oct-13-2025-08-15-15-8067-PM.png)](https://blog.quelimaging.com/iad-overview) [concepts](https://blog.quelimaging.com/tag/concepts) ### [Inverse-Adding-Doubling Algorithm: Translating measurements into models](https://blog.quelimaging.com/iad-overview) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) We discussed before how raw reflectance and transmittance spectra provide a story of a photon's... [Read more](https://blog.quelimaging.com/iad-overview) [![Illustration of a general spectrophotometry configured with two integrating spheres. Most commercial spectrophotometers only contain one integrating sphere. ](https://blog.quelimaging.com/hubfs/undefined-Oct-13-2025-06-50-47-0324-PM.png)](https://blog.quelimaging.com/spectrophotometry-overview) [concepts](https://blog.quelimaging.com/tag/concepts) ### [Full-Spectrum Optical Measurements in Tissue and Phantoms](https://blog.quelimaging.com/spectrophotometry-overview) ![Picture of The QUEL Team](https://blog.quelimaging.com/hs-fs/hubfs/QUEL_Q.png?width=50&name=QUEL_Q.png) [The QUEL Team](https://blog.quelimaging.com/author/quel) If you're building an optical medical device (e.g., pulse oximeters, surgical guidance tools,... 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